ProBio 12+

Point Detection of Biological Warfare Agents & Hazards

The Biodefence market requires a system to detect and identify biological warfare agents and hazards with the highest sensitivity, the highest selectivity, maximum speed and accuracy. OWR’s ProBio 12+ is the first tool that combines these features for military, homeland security and biosafety applications.

Summary

OWR’s ProBio 12+ integrates nucleic acid tests (PCR) and immunoassays (ELISA) on one single platform. The user-friendly system enables quick point detection of the most relevant bacteria and toxins. Detection results provide the utmost level of reliability.

Currently the ProBio 12+ detects the following BWAs:

Bacillus anthracis, Francisella tularensis, Yersinia pestis, Botulinum Toxin, Rizin, Staphylococcus Enterotoxin B

Further applications, particularly for the detection of other organic hazards known as the “dirty dozen” are currently developed.

Virus tests upon request.
Analysis Workflow
Sample collection, specific sample preparation and transfer of purified sample to ProBio Cartridge.
Cartridge transfer into the instrument.

ProBio 12+ Cartridge

All elements that are essential for the respective test are combined in a single disposable cartridge. The cartridge is a completely encased micro reactor. The cartridge concept supports implementation of nucleic acid base tests (PCR, Hybridization) and immunological test formats (ELISA). Detection is being carried out optically by the analysis of specific binding patterns on the integrated probe

Analysis Workflow

Test Methods
Amplification (PCR) for bacteria
Immunoassays (ELISA) for toxins
Sample preparation

Overview

Results within less than one hour after sample preparation
Parallel search (Multiplex) for different agents
Minimal detection limit
Lowest rate of false-positive results
Automated system
Independent from laboratory environment
No medical or biological specialist knowledge necessary